Higher CSF Levels of NLRP3 Inflammasome Is Associated With Poor Prognosis of Anti-N-methyl-D-Aspartate Receptor Encephalitis

Higher CSF Levels of NLRP3 Inflammasome Is Associated With Poor Prognosis of Anti-N-methyl-D-Aspartate Receptor Encephalitis

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is accepted as an autoimmune disorder of the central nervous system (CNS). NLR family pyrin domain containing 3 (NLRP3) inflammasome, a potent innate inflammatory mediator, can activate IL-1β and induce the migration of T helper cell into CNS....

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Bibliographic Details
Main Authors: Yu Peng, Baozhu Liu, Shanshan Pei, Dong Zheng, Zhanhang Wang, Teng Ji, Suyue Pan, Hai-Ying Shen, Honghao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
anti-NMDAR encephalitis
neuro-inflammation
cytokine
NLRP3
modified Rankin Scale
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00905/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00905/full

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