Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration.

Epidermal lineages and injury induced regeneration are controlled by transcriptional programs coordinating cellular signaling and epigenetic regulators, but the mechanism remains unclear. Previous studies showed that conditional deletion of the transcriptional coactivator Mediator 1 (Med1) changes e...

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Bibliographic Details
Main Authors: Yuko Oda, Thai Nguyen, Akiko Hata, Mark B Meyer, J Wesley Pike, Daniel D Bikle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238076