Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

Objective: Parental obesity can induce metabolic phenotypes in offspring independent of the inherited DNA sequence. Here we asked whether such non-genetic acquired metabolic traits can be passed on to a second generation that has never been exposed to obesity, even as germ cells. Methods: We examine...

Full description

Bibliographic Details
Main Authors: Jennifer E. Cropley, Sally A. Eaton, Alastair Aiken, Paul E. Young, Eleni Giannoulatou, Joshua W.K. Ho, Michael E. Buckland, Simon P. Keam, Gyorgy Hutvagner, David T. Humphreys, Katherine G. Langley, Darren C. Henstridge, David I.K. Martin, Mark A. Febbraio, Catherine M. Suter
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816300710

Internet

http://www.sciencedirect.com/science/article/pii/S2212877816300710

Similar Items