Evidence for positive selection on the Osteogenin (BMP3) gene in human populations.

BACKGROUND: Human skeletal system has evolved rapidly since the dispersal of modern humans from Africa, potentially driven by selection and adaptation. Osteogenin (BMP3) plays an important role in skeletal development and bone osteogenesis as an antagonist of the osteogenic bone morphogenetic protei...

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Bibliographic Details
Main Authors: Dong-Dong Wu, Wei Jin, Xiao-Dan Hao, Nelson Leung Sang Tang, Ya-Ping Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2881034?pdf=render