Cell surface engineering of Bacillus subtilis improves production yields of heterologously expressed α-amylases

Cell surface engineering of Bacillus subtilis improves production yields of heterologously expressed α-amylases

Abstract Background Bacillus subtilis is widely used as a cell factory for numerous heterologous proteins of commercial value and medical interest. To explore the possibility of further enhancing the secretion potential of this model bacterium, a library of engineered strains with modified cell surf...

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Bibliographic Details
Main Authors: Haojie Cao, Auke J. van Heel, Hifza Ahmed, Maarten Mols, Oscar P. Kuipers
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Microbial Cell Factories
Subjects:
Bacillus
Protein secretion
α-Amylases
Electrostatic interaction
PssA
ClsA
Online Access:http://link.springer.com/article/10.1186/s12934-017-0674-0

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http://link.springer.com/article/10.1186/s12934-017-0674-0

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