Evolution from small molecule to nano-drug delivery systems: An emerging approach for cancer therapy of ursolic acid

Ursolic acid (UA), a natural pentacyclic triterpenoid, possesses widespread biological and pharmacological activities. However, drawbacks such as low bioavailability, poor targeting and rapid metabolism greatly hinder its further clinical application. Recently, with the development of nanotechnology...

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Bibliographic Details
Main Authors: Jingwei Shao, Yifan Fang, Ruirui Zhao, Fangmin Chen, Mingyue Yang, Jiali Jiang, Zixuan Chen, Xiaotian Yuan, Lee Jia
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087619306816