MntC-Dependent Manganese Transport Is Essential for Staphylococcus aureus Oxidative Stress Resistance and Virulence

Work outlined in this report demonstrated that MntC-dependent manganese transport is required for S. aureus virulence. These study results support the model that MntC-specific antibodies elicited by a vaccine have the potential to disrupt S. aureus manganese transport and thus abrogate to its virule...

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Bibliographic Details
Main Authors: Luke D. Handke, Alexey V. Gribenko, Yekaterina Timofeyeva, Ingrid L. Scully, Annaliesa S. Anderson
Format: Article
Language:English
Published: American Society for Microbiology 2018-07-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00336-18