An intracellular membrane protein GEP1 regulates xanthurenic acid induced gametogenesis of malaria parasites

An intracellular membrane protein GEP1 regulates xanthurenic acid induced gametogenesis of malaria parasites

Mosquito-derived xanthurenic acid (XA) is a trigger for gametogenesis of Plasmodium parasites. Here the authors show that the putative amino acid transporter GEP1 is required for XA-stimulated gametogenesis in Plasmodium yoelii and that it interacts with guanylyl cyclase α (GCα), a cGMP synthesizing...

Full description

Bibliographic Details
Main Authors: Yuanyuan Jiang, Jun Wei, Huiting Cui, Chuanyuan Liu, Yuan Zhi, ZhengZheng Jiang, Zhenkui Li, Shaoneng Li, Zhenke Yang, Xu Wang, Pengge Qian, Cui Zhang, Chuanqi Zhong, Xin-zhuan Su, Jing Yuan
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15479-3

Internet

https://doi.org/10.1038/s41467-020-15479-3

Similar Items