Combined Oral Fentanyl Citrate and Midazolam as Premedication for Bone Marrow Aspiration and Biopsy in Patients with Hematological Malignancies: A Randomized, Controlled and Patient-Blinded Clinical Trial

Combined Oral Fentanyl Citrate and Midazolam as Premedication for Bone Marrow Aspiration and Biopsy in Patients with Hematological Malignancies: A Randomized, Controlled and Patient-Blinded Clinical Trial

Bone marrow aspiration and biopsy (BMAB) is a painful procedure, and the routinely used local infiltration anesthesia (LIA) with lidocaine is unable to provide pain relief during the most uncomfortable phases. The primary endpoint of the present randomized, patient-blinded trial was to evaluate the...

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Bibliographic Details
Main Authors: Claudio Cerchione, Giovanni Martinelli, Marco Picardi, Novella Pugliese, Davide Nappi, Aniello Casoria, Angela Gravetti, Delia Cangini, Maria Benedetta Giannini, Sonia Ronconi, Giorgia Simonetti, Andrea Ghelli Luserna Di Rorà, Ugo De Giorgi, Mattia Altini, Sara Bravaccini, Ilaria Santoriello, Cristiano Minucci, Fabrizio Pane, Vincenzo Martinelli
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Journal of Clinical Medicine
Subjects:
bone marrow aspiration and biopsy
pain
analgesia
anxiolysis
fentanyl citrate
Online Access:https://www.mdpi.com/2077-0383/9/2/395

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https://www.mdpi.com/2077-0383/9/2/395

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