Pharmacogenetics may influence tacrolimus daily dose, but not urinary tubular damage markers in the long-term period after renal transplantation

Pharmacogenetics may influence tacrolimus daily dose, but not urinary tubular damage markers in the long-term period after renal transplantation

Background: The primary goal of this study was to evaluate the influence of cytochrome P450 (CYP) 3A5 (6986A>G) and ABCB1 (3435C>T) polymorphisms on tacrolimus (TAC) dosage regimen and exposure. Second, we evaluated the influence of TAC dosage regimen and the tested polymorphisms on renal oxid...

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Bibliographic Details
Main Authors: Stefanović Nikola Z., Cvetković Tatjana P., Veličković-Radovanović Radmila M., Jevtović-Stoimenov Tatjana M., Vlahović Predrag M., Stojanović Ivana R., Pavlović Dušica D.
Format: Article
Language:English
Published: Society of Medical Biochemists of Serbia, Belgrade 2015-01-01
Series:Journal of Medical Biochemistry
Subjects:
abcb1
cyp3a5
oxidative stress
renal transplantation
tacrolimus
tubular damage
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2015/1452-82581504422S.pdf

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https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2015/1452-82581504422S.pdf

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