Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization.

Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization.

CCHCR1 (Coiled-Coil α-Helical Rod protein 1), within the major psoriasis susceptibility locus PSORS1, is a plausible candidate gene with the psoriasis associated risk allele CCHCR1*WWCC. Although its expression pattern in psoriatic skin differs from healthy skin and its overexpression influences cel...

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Bibliographic Details
Main Authors: Mari H Tervaniemi, H Annika Siitonen, Cilla Söderhäll, Gurinder Minhas, Jyrki Vuola, Inkeri Tiala, Raija Sormunen, Lena Samuelsson, Sari Suomela, Juha Kere, Outi Elomaa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23189171/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23189171/?tool=EBI

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