Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313 [version 1; peer review: 2 approved]

Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313 [version 1; peer review: 2 approved]

Background: Salmonella Typhimurium ST313 exhibits signatures of adaptation to invasive human infection, including higher resistance to humoral immune responses than gastrointestinal isolates. Full resistance to antibody-mediated complement killing (serum resistance) among nontyphoidal Salmonellae is...

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Bibliographic Details
Main Authors: Edna M. Ondari, Elizabeth J. Klemm, Chisomo L. Msefula, Moataz Abd El Ghany, Jennifer N. Heath, Derek J. Pickard, Lars Barquist, Gordon Dougan, Robert A. Kingsley, Calman A. MacLennan
Format: Article
Language:English
Published: Wellcome 2019-04-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-74/v1

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https://wellcomeopenresearch.org/articles/4-74/v1

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