Small Molecule Inhibitors of CXCR4

<p>CXCR4 is a G-protein-coupled receptor involved in a number of physiological processes in the hematopoietic and immune systems. The SDF-1/CXCR4 axis is significantly associated with several diseases, such as HIV, cancer, WHIM syndrome, rheumatoid arthritis, pulmonary fibrosis and lupus. For...

Full description

Bibliographic Details
Main Author: Bikash Debnath, Shili Xu, Fedora Grande, Antonio Garofalo, Nouri Neamati
Format: Article
Language:English
Published: Ivyspring International Publisher 2013-01-01
Series:Theranostics
Online Access:http://www.thno.org/v03p0047.htm