Modulation of T-cell responses by anti-tumor necrosis factor treatments in rheumatoid arthritis: a review

Abstract Tumor necrosis factor (TNF) is a pleiotropic cytokine involved in many aspects of immune regulation. Anti-TNF biological therapy has been considered a breakthrough in the treatment of chronic autoimmune diseases, such as rheumatoid arthritis (RA). In this review, because of the major involv...

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Bibliographic Details
Main Authors: Jean-Luc Davignon, Benjamin Rauwel, Yannick Degboé, Arnaud Constantin, Jean-Fredéric Boyer, Andrey Kruglov, Alain Cantagrel
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13075-018-1725-6