Multiple Strategies for Translesion Synthesis in Bacteria

Damage to DNA is common and can arise from numerous environmental and endogenous sources. In response to ubiquitous DNA damage, Y-family DNA polymerases are induced by the SOS response and are capable of bypassing DNA lesions. In Escherichia coli, these Y-family polymerases are DinB and UmuC, whose...

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Bibliographic Details
Main Authors: Penny J. Beuning, Kathryn M. Jones, Paul J. Ippoliti, Nicholas A. DeLateur
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Cells
Subjects:
2C)
Online Access:http://www.mdpi.com/2073-4409/1/4/799