Vi4-miR-185-5p-Igfbp3 Network Protects the Brain From Neonatal Hypoxic Ischemic Injury via Promoting Neuron Survival and Suppressing the Cell Apoptosis

Vi4-miR-185-5p-Igfbp3 Network Protects the Brain From Neonatal Hypoxic Ischemic Injury via Promoting Neuron Survival and Suppressing the Cell Apoptosis

Neonatal hypoxic ischemic encephalopathy (HIE) due to birth asphyxia is common and causes severe neurological deficits, without any effective therapies currently available. Neuronal death is an important driving factors of neurological disorders after HIE, but the regulatory mechanisms are still unc...

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Bibliographic Details
Main Authors: Liu-Lin Xiong, Lu-Lu Xue, Ruo-Lan Du, Hao-Li Zhou, Ya-Xin Tan, Zheng Ma, Yuan Jin, Zi-Bin Zhang, Yang Xu, Qiao Hu, Larisa Bobrovskaya, Xin-Fu Zhou, Jia Liu, Ting-Hua Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hypoxic ischemic encephalopathy
Vi4
miRNA-185-5p
IGFBP3
neuron survival
cell apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.529544/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.529544/full

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