Reduced basal ATP synthetic flux of skeletal muscle in patients with previous acromegaly.

Reduced basal ATP synthetic flux of skeletal muscle in patients with previous acromegaly.

BACKGROUND: Impaired mitochondrial function and ectopic lipid deposition in skeletal muscle and liver have been linked to decreased insulin sensitivity. As growth hormone (GH) excess can reduce insulin sensitivity, we examined the impact of previous acromegaly (AM) on glucose metabolism, lipid stora...

Full description

Bibliographic Details
Main Authors: Julia Szendroedi, Elisabeth Zwettler, Albrecht Ingo Schmid, Marek Chmelik, Giovanni Pacini, Gertrud Kacerovsky, Gerhard Smekal, Peter Nowotny, Oswald Wagner, Christoph Schnack, Guntram Schernthaner, Klaus Klaushofer, Michael Roden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2599885?pdf=render

Internet

http://europepmc.org/articles/PMC2599885?pdf=render

Similar Items