ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells

ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells

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<p>Abstract</p> <p>Background</p> <p>The extracellular matrix (ECM) has a key role in facilitating the progression of ovarian cancer and we have shown recently that the secreted ECM protein TGFBI modulates the response of ovarian cancer to paclitaxel-induced cell death....

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Bibliographic Details
Main Authors: Tumbarello David A, Temple Jillian, Brenton James D
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Molecular Cancer
Subjects:
Chemotherapy
Cell adhesion
Ovarian cancer
Integrin receptor
Extracellular matrix
Online Access:http://www.molecular-cancer.com/content/11/1/36

Internet

http://www.molecular-cancer.com/content/11/1/36

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