Efficacy and Safety of Neoadjuvant Targeted Therapy vs. Neoadjuvant Chemotherapy for Stage IIIA EGFR-Mutant Non-small Cell Lung Cancer: A Systematic Review and Meta-Analysis

Efficacy and Safety of Neoadjuvant Targeted Therapy vs. Neoadjuvant Chemotherapy for Stage IIIA EGFR-Mutant Non-small Cell Lung Cancer: A Systematic Review and Meta-Analysis

Purpose: The role of targeted therapy in the neoadjuvant field of stage IIIA epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC) is still controversial. We sought to evaluate the efficacy and safety of neoadjuvant targeted therapy (NTT) with neoadjuvant chemo...

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Bibliographic Details
Main Authors: Dong Chen, Zixian Jin, Jian Zhang, Congcong Xu, Kanghao Zhu, Yuhang Ruan, Bo Zhang, Baofu Chen, Jianfei Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Surgery
Subjects:
non-small cell lung cancer
neoadjuvant therapy
chemotherapy
molecular targeted therapy
epidermal growth factor receptor
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2021.715318/full

Internet

https://www.frontiersin.org/articles/10.3389/fsurg.2021.715318/full

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