Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro.

BACKGROUND:Mammalian cardiac myocytes withdraw from the cell cycle during post-natal development, resulting in a non-proliferating, fully differentiated adult phenotype that is unable to repair damage to the myocardium, such as occurs following a myocardial infarction. We and others previously have...

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Bibliographic Details
Main Authors: Carmen H Coxon, Katrina A Bicknell, Fleur L Moseley, Gavin Brooks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2727448?pdf=render