Arsenic Trioxide Inhibits Cell Growth and Induces Apoptosis through Inactivation of Notch Signaling Pathway in Breast Cancer

Arsenic Trioxide Inhibits Cell Growth and Induces Apoptosis through Inactivation of Notch Signaling Pathway in Breast Cancer

Arsenic trioxide has been reported to inhibit cell growth and induce apoptotic cell death in many human cancer cells including breast cancer. However, the precise molecular mechanisms underlying the anti-tumor activity of arsenic trioxide are still largely unknown. In the present study, we assessed...

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Bibliographic Details
Main Authors: Zhiwei Wang, Fazlul H Sarkar, Lucio Miele, Aamir Ahmad, Bin Bao, Zhiwen Chen, Chuanzhong Mei, Qingling Yang, Jun Xia, Youjian Li
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:International Journal of Molecular Sciences
Subjects:
Notch
arsenic trioxide
NF-κB
breast cancer
apoptosis
cell growth
Online Access:http://www.mdpi.com/1422-0067/13/8/9627

Internet

http://www.mdpi.com/1422-0067/13/8/9627

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