Signatures of immune reprogramming in anti-CD52 therapy of MS: markers for risk stratification and treatment response

Abstract Background Multiple sclerosis is one of the most prevalent neurological diseases in young adults affecting over 2 million people worldwide. Alemtuzumab is a highly effective therapy in relapsing remitting MS. Alemtuzumab is a monoclonal CD52 antibody that proved its efficacy against an acti...

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Bibliographic Details
Main Authors: Laura Bierhansl, Tobias Ruck, Steffen Pfeuffer, Catharina C. Gross, Heinz Wiendl, Sven G. Meuth
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Neurological Research and Practice
Subjects:
Online Access:https://doi.org/10.1186/s42466-019-0045-x