CAT, GPX1, MnSOD, GSTM1, GSTT1, and GSTP1 Genetic Polymorphisms in Chronic Myeloid Leukemia: A Case-Control Study

Oxidative damage at the DNA level may be promoted by high levels of reactive oxygen species (ROS), leading to genomic instability and increased neoplastic risk. Superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase (CAT) enzymes are implicated in the prevention of DNA damage by ROS....

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Bibliographic Details
Main Authors: Claudia Bănescu, Adrian P. Trifa, Septimiu Voidăzan, Valeriu G. Moldovan, Ioan Macarie, Erzsebeth Benedek Lazar, Delia Dima, Carmen Duicu, Minodora Dobreanu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2014/875861