Age-Related Left Ventricular Changes and Their Association with Leukocyte Telomere Length in Healthy People.

With advancing age the left ventricle (LV) undergoes structural and functional changes, thereby creating the substrate for the development of diseases. One possible mechanism of the ageing heart is a cellular senescence. Leukocyte telomere length (LTL) is a marker of replicative ageing. The purpose...

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Bibliographic Details
Main Authors: Dariga U Akasheva, Ekaterina V Plokhova, Olga N Tkacheva, Irina D Strazhesko, Ekaterina N Dudinskaya, Anna S Kruglikova, Valentina S Pykhtina, Natalia V Brailova, Inna A Pokshubina, Natalia V Sharashkina, Mikhail V Agaltsov, Dmitry Skvortsov, Sergey A Boytsov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4537122?pdf=render