Cartilage Protective and Immunomodulatory Features of Osteoarthritis Synovial Fluid-Treated Adipose-Derived Mesenchymal Stem Cells Secreted Factors and Extracellular Vesicles-Embedded miRNAs

Cartilage Protective and Immunomodulatory Features of Osteoarthritis Synovial Fluid-Treated Adipose-Derived Mesenchymal Stem Cells Secreted Factors and Extracellular Vesicles-Embedded miRNAs

Intra-articular administration of adipose-derived mesenchymal stem cells (ASCs), either in vitro expanded or within adipose tissue-based products obtained at point-of-care, has gained popularity as innovative regenerative medicine approach for osteoarthritis (OA) treatment. ASCs can stimulate tissue...

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Bibliographic Details
Main Authors: Enrico Ragni, Alessandra Colombini, Marco Viganò, Francesca Libonati, Carlotta Perucca Orfei, Luigi Zagra, Laura de Girolamo
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
osteoarthritis
synovial fluid
ASCs
secretome
extracellular vesicles
miRNAs
Online Access:https://www.mdpi.com/2073-4409/10/5/1072

Internet

https://www.mdpi.com/2073-4409/10/5/1072

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