An intrinsic cell cycle timer terminates limb bud outgrowth
The longstanding view of how proliferative outgrowth terminates following the patterning phase of limb development involves the breakdown of reciprocal extrinsic signalling between the distal mesenchyme and the overlying epithelium (e-m signalling). However, by grafting distal mesenchyme cells from...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/37429 |