Role of high-risk antibiotic use in incidence of health-care-associated Clostridioides difficile infection in Quebec, Canada: a population-level ecological study

Summary: Background: The incidence of health-care-associated Clostridioides difficile infections has been declining in the Canadian province of Quebec since 2015. We examined whether changes in high-risk antibiotic use could account for this decrease, as reported in other jurisdictions. Methods: We...

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Main Authors: Elise Fortin, PhD, Daniel J G Thirion, ProfPharmD, Manale Ouakki, MSc, Christophe Garenc, PhD, Cindy Lalancette, PhD, Luc Bergeron, MSc, Danielle Moisan, MD, Jasmin Villeneuve, MD, Yves Longtin, MD, Daniel Bolduc, Charles Frenette, Lise-Andrée Galarneau, Christophe Garenc, Cindy Lalancette, Yves Longtin, Vivian Loo, Muleka Ngenda Muadi, Natasha Parisien, Isabelle Rouleau, Noémie Savard, Josée Vachon, Jasmin Villeneuve
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:The Lancet Microbe
Online Access:http://www.sciencedirect.com/science/article/pii/S2666524721000057