Steroid resistance in COPD? Overlap and differential anti-inflammatory effects in smokers and ex-smokers.

Steroid resistance in COPD? Overlap and differential anti-inflammatory effects in smokers and ex-smokers.

Inhaled corticosteroids (ICS) reduce exacerbation rates and improve health status but can increase the risk of pneumonia in COPD. The GLUCOLD study, investigating patients with mild-to-moderate COPD, has shown that long-term (2.5-year) ICS therapy induces anti-inflammatory effects. The literature su...

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Bibliographic Details
Main Authors: Susan J M Hoonhorst, Nick H T ten Hacken, Judith M Vonk, Wim Timens, Pieter S Hiemstra, Thérèse S Lapperre, Peter J Sterk, Dirkje S Postma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914834?pdf=render

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http://europepmc.org/articles/PMC3914834?pdf=render

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