Steroid resistance in COPD? Overlap and differential anti-inflammatory effects in smokers and ex-smokers.
Inhaled corticosteroids (ICS) reduce exacerbation rates and improve health status but can increase the risk of pneumonia in COPD. The GLUCOLD study, investigating patients with mild-to-moderate COPD, has shown that long-term (2.5-year) ICS therapy induces anti-inflammatory effects. The literature su...
Main Authors: | Susan J M Hoonhorst, Nick H T ten Hacken, Judith M Vonk, Wim Timens, Pieter S Hiemstra, Thérèse S Lapperre, Peter J Sterk, Dirkje S Postma |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3914834?pdf=render |
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