Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy

Dexamethasone, a widely used corticosteroid, has recently been reported as the first drug to increase the survival chances of patients with severe COVID-19. Therapeutic agents, including dexamethasone, are mostly transported through the body by binding to serum albumin. Here, the first structure of...

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Bibliographic Details
Main Authors: Ivan G. Shabalin, Mateusz P. Czub, Karolina A. Majorek, Dariusz Brzezinski, Marek Grabowski, David R. Cooper, Mateusz Panasiuk, Maksymilian Chruszcz, Wladek Minor
Format: Article
Language:English
Published: International Union of Crystallography 2020-11-01
Series:IUCrJ
Subjects:
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252520012944