Hypoxic-ischemic injury decreases anxiety-like behavior in rats when associated with loss of tyrosine-hydroxylase immunoreactive neurons of the substantia nigra

Hypoxic-ischemic injury decreases anxiety-like behavior in rats when associated with loss of tyrosine-hydroxylase immunoreactive neurons of the substantia nigra

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Neonatal Sprague-Dawley rats were randomly divided into normal control, mild hypoxia-ischemia (HI), and severe HI groups (N = 10 in each group at each time) on postnatal day 7 (P7) to study the effect of mild and severe HI on anxiety-like behavior and the expression of tyrosine hydroxylase (TH) in t...

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Bibliographic Details
Main Authors: Hei Ming-Yan, Ya-Li Luo, Xiao-Chun Zhang, Hong Liu, Ru Gao, Jing-Jiang Wu
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Anxiety
Tyrosine hydroxylase
Substantia nigra
Hypoxia-ischemia
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100003

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100003

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