Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

<p>Abstract</p> <p>Background</p> <p>Hematopoietic stem cell transplantation is increasingly performed for hematologic diseases. As a major side effect, acute graft versus host disease (GvHD) with serious gastrointestinal symptoms including diarrhea, gastrointestinal bl...

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Bibliographic Details
Main Authors: Rosenstiel Philip, Bewig Burkhard, Hampe Jochen, Häsler Robert, Ellrichmann Mark, Kruse Marie-Luise, Stüber Eckhard, Lange-Grumfeld Julia, Noth Rainer, Schreiber Stefan, Arlt Alexander
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/11/109