Allostasis and sedation practices in intensive care evaluation: an observational pilot study

Abstract Background A dysregulated stress response has been implicated in the pathogenesis of critical illness. Sedative agents utilised in the critically unwell patient may impact upon the stress response with a downstream negative effect on multiple organ systems. This study was designed to assess...

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Bibliographic Details
Main Authors: John P. R. Moore, Chris Anstey, Lauren Murray, John F. Fraser, Mervyn Singer
Format: Article
Language:English
Published: SpringerOpen 2018-06-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40635-018-0179-0