Mycobacterium tuberculosis lineage influences innate immune response and virulence and is associated with distinct cell envelope lipid profiles.

The six major genetic lineages of Mycobacterium tuberculosis are strongly associated with specific geographical regions, but their relevance to bacterial virulence and the clinical consequences of infection are unclear. Previously, we found that in Vietnam, East Asian/Beijing and Indo-Oceanic strain...

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Main Authors: Nitya Krishnan, Wladimir Malaga, Patricia Constant, Maxine Caws, Thi Hoang Chau Tran, Jenifer Salmons, Thi Ngoc Lan Nguyen, Duc Bang Nguyen, Mamadou Daffé, Douglas B Young, Brian D Robertson, Christophe Guilhot, Guy E Thwaites
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3169546?pdf=render