Trichinella spiralis Thioredoxin Peroxidase 2 Regulates Protective Th2 Immune Response in Mice by Directly Inducing Alternatively Activated Macrophages

Trichinella spiralis Thioredoxin Peroxidase 2 Regulates Protective Th2 Immune Response in Mice by Directly Inducing Alternatively Activated Macrophages

Trichinella infection can induce macrophages into the alternatively activated phenotype, which is primarily associated with the development of a polarized Th2 immune response. In the present study, we examined the immunomodulatory effect of T. spiralis thioredoxin peroxidase-2 (TsTPX2), a protein de...

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Bibliographic Details
Main Authors: Qi-Wang Jin, Nian-Zhang Zhang, Wen-Hui Li, Hong-Tao Qin, Yin-Ju Liu, John Asekhaen Ohiolei, Dong-Yu Niu, Hong-Bin Yan, Li Li, Wan-Zhong Jia, Ming-Xin Song, Bao-Quan Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
Trichinella spiralis
thioredoxin peroxidase-2
Th2 immune responses
macrophage
alternative activation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02015/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02015/full

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