Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).Methods: Blood samples were collected from 20 patients with NMOSD and 17 patients with MS, as well as from 15 p...

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Bibliographic Details
Main Authors: Lennard Ostendorf, Ronja Mothes, Sofie van Koppen, Randall L. Lindquist, Judith Bellmann-Strobl, Susanna Asseyer, Klemens Ruprecht, Tobias Alexander, Raluca A. Niesner, Anja E. Hauser, Friedemann Paul, Helena Radbruch
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
low-density granulocytes
multiple sclerosis
neuromyelitis optica
neuroinflammation
autoimmunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02725/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02725/full

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