Optimal concentration and time window for proliferation and differentiation of neural stem cells from embryonic cerebral cortex: 5% oxygen preconditioning for 72 hours

Optimal concentration and time window for proliferation and differentiation of neural stem cells from embryonic cerebral cortex: 5% oxygen preconditioning for 72 hours

Hypoxia promotes proliferation and differentiation of neural stem cells from embryonic day 12 rat brain tissue, but the concentration and time of hypoxic preconditioning are controversial. To address this, we cultured neural stem cells isolated from embryonic day 14 rat cerebral cortex in 5% and 10%...

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Bibliographic Details
Main Authors: Li-li Yuan, Ying-jun Guan, Deng-dian Ma, Hong-mei Du
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; brain injury; neural stem cells; low oxygen; cerebral cortex; apoptosis; differentiation; microtubule-associated protein 2; glial fibrillary acidic protein; caspase-3; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=9;spage=1516;epage=1522;aulast=Yuan

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=9;spage=1516;epage=1522;aulast=Yuan

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