Host nectin-1 is required for efficient Chlamydia trachomatis serovar E development.

Host nectin-1 is required for efficient Chlamydia trachomatis serovar E development.

Interaction of Herpes Simplex Virus (HSV) glycoprotein D (gD) with the host cell surface during Chlamydia trachomatis/HSV co-infection stimulates chlamydiae to become persistent. During viral entry, gD interacts with one of 4 host co-receptors: HVEM (herpes virus entry mediator), nectin-1, nectin-2...

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Bibliographic Details
Main Authors: Jennifer Vanover Hall, Jingru eSun, Jessica eSlade, Jennifer eKintner, Marissa eBambino, Judy eWhittimore, Robert V. Schoborg
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Chlamydia trachomatis
Persistence
Co-infection
Herpes Simplex Virus
chlamydial stress response
Nectin-1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00158/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00158/full

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