Formulation and Optimization of Butenafine-Loaded Topical Nano Lipid Carrier-Based Gel: Characterization, Irritation Study, and Anti-Fungal Activity

Formulation and Optimization of Butenafine-Loaded Topical Nano Lipid Carrier-Based Gel: Characterization, Irritation Study, and Anti-Fungal Activity

The present study aims to prepare and optimize butenafine hydrochloride NLCs formulation using solid and liquid lipid. The optimized selected BF-NLCopt was further converted into Carbopol-based gel for topical application for the treatment of fungal infection. Box Behnken design was employed to opti...

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Bibliographic Details
Main Authors: Wael A. Mahdi, Sarah I. Bukhari, Syed Sarim Imam, Sultan Alshehri, Ameeduzzafar Zafar, Mohd Yasir
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
butenafine
NLCs
topical gel
anti-fungal
optimization
irritation study
Online Access:https://www.mdpi.com/1999-4923/13/7/1087

Internet

https://www.mdpi.com/1999-4923/13/7/1087

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