The Addition of Sirolimus to GVHD Prophylaxis After Allogeneic Hematopoietic Stem Cell Transplantation: A Meta-Analysis of Efficacy and Safety

The Addition of Sirolimus to GVHD Prophylaxis After Allogeneic Hematopoietic Stem Cell Transplantation: A Meta-Analysis of Efficacy and Safety

ObjectiveThe objective of this study was to evaluate the safety and efficacy of sirolimus (SRL) in the prevention of graft-versus-host disease (GVHD) in recipients following allogeneic hematopoietic stem cell transplantation (allo-HSCT).MethodsRandomized controlled trials (RCTs) evaluating the safet...

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Bibliographic Details
Main Authors: Xiaoli Chen, Hengrui Sun, Kaniel Cassady, Shijie Yang, Ting Chen, Li Wang, Hongju Yan, Xi Zhang, Yimei Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
sirolimus
GVHD
HSCT
prophylaxis
TMA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.683263/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.683263/full

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