Pelota regulates the development of extraembryonic endoderm through activation of bone morphogenetic protein (BMP) signaling

Pelota (Pelo) is ubiquitously expressed, and its genetic deletion in mice leads to embryonic lethality at an early post-implantation stage. In the present study, we conditionally deleted Pelo and showed that PELO deficiency did not markedly affect the self-renewal of embryonic stem cells (ESCs) or t...

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Bibliographic Details
Main Authors: Gunsmaa Nyamsuren, Aleksandra Kata, Xingbo Xu, Priyadharsini Raju, Ralf Dressel, Wolfgang Engel, D.V. Krishna Pantakani, Ibrahim M. Adham
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114000476