Upregulation of IGF-1R expression during neoadjuvant therapy predicts poor outcome in breast cancer patients.

Upregulation of IGF-1R expression during neoadjuvant therapy predicts poor outcome in breast cancer patients.

The insulin-like growth factor 1 receptor (IGF-1R) may be involved in the development of resistance against conventional cancer treatment. The aim of this study was to assess whether IGF-1R expression of breast tumors changes during neoadjuvant therapy and to study whether these changes were associa...

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Bibliographic Details
Main Authors: Sandra Heskamp, Otto C Boerman, Janneke D M Molkenboer-Kuenen, Carla A Wauters, Luc J A Strobbe, Caroline M P W Mandigers, Peter Bult, Wim J G Oyen, Winette T A van der Graaf, Hanneke W M van Laarhoven
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4334229?pdf=render

Internet

http://europepmc.org/articles/PMC4334229?pdf=render

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