No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis

No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis

BackgroundReduced heart rate (HR) increase (HRI), recovery (HRR), and higher resting HR are associated with cardiovascular (CV) disease, but causal inferences have not been deduced. We investigated causal effects of HRI, HRR, and resting HR on CV risk, all-cause mortality (ACM), atrial fibrillation...

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Bibliographic Details
Main Authors: Josephine Mensah-Kane, Amand F. Schmidt, Aroon D. Hingorani, Chris Finan, Yutang Chen, Stefan van Duijvenboden, Michele Orini, Pier D. Lambiase, Andrew Tinker, Eirini Marouli, Patricia B. Munroe, Julia Ramírez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
heart rate
Mendelian randomization
GWAS
cardiovascular risk
recovery
exercise
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.569323/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.569323/full

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