Short‐term intermittent hypoxia induces simultaneous systemic insulin resistance and higher cardiac contractility in lean mice

Short‐term intermittent hypoxia induces simultaneous systemic insulin resistance and higher cardiac contractility in lean mice

Abstract Background Intermittent hypoxia (IH) is the major feature of obstructive sleep apnea syndrome, well‐known to induce cardiometabolic complications. We previously demonstrated that IH induces hyperinsulinemia and associated altered insulin signaling in adipose tissue, liver, and skeletal musc...

Full description

Bibliographic Details
Main Authors: Maximin Détrait, Mélanie Pesse, Clément Calissi, Sophie Bouyon, Jacques Brocard, Guillaume Vial, Jean‐Louis Pépin, Elise Belaidi, Claire Arnaud
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Physiological Reports
Subjects:
cardiac function
cardiac remodeling
hyperinsulinemia
intermittent hypoxia
obstructive sleep apnea
Online Access:https://doi.org/10.14814/phy2.14738

Internet

https://doi.org/10.14814/phy2.14738

Similar Items