Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

<p>Abstract</p> <p>Background</p> <p>Somatic mutations of mitochondrial DNA (mtDNA) are common in many human cancers. We have described an oligonucleotide microarray ("MitoChip") for rapid sequencing of the entire mitochondrial genome (Zhou et al, <it>J...

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Bibliographic Details
Main Authors: Montgomery Elizabeth A, Eshleman James R, Lee Edward E, Canto Marcia, Wang Jean, Zhou Shaoyu, Sui Guoping, Sidransky David, Califano Joseph A, Maitra Anirban
Format: Article
Language:English
Published: BMC 2006-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/73

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http://www.molecular-cancer.com/content/5/1/73

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