Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens

Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens

Clostridium scindens American Type Culture Collection 35704 is capable of converting primary bile acids to toxic secondary bile acids, as well as converting glucocorticoids to androgens by side-chain cleavage. The molecular structure of the side-chain cleavage product of cortisol produced by C. scin...

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Bibliographic Details
Main Authors: Jason M. Ridlon, Shigeo Ikegawa, João M.P. Alves, Biao Zhou, Akiko Kobayashi, Takashi Iida, Kuniko Mitamura, Genzoh Tanabe, Myrna Serrano, Ainee De Guzman, Patsy Cooper, Gregory A. Buck, Phillip B. Hylemon
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Journal of Lipid Research
Subjects:
RNA-Seq
microbiome
steroid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520351336

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520351336

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