The class I myosin MYO1D binds to lipid and protects against colitis

Myosin ID (MYO1D) is a member of the class I myosin family. We screened 48,649 third generation (G3) germline mutant mice derived from N-ethyl-N-nitrosourea-mutagenized grandsires for intestinal homeostasis abnormalities after oral administration of dextran sodium sulfate (DSS). We found and validat...

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Bibliographic Details
Main Authors: William McAlpine, Kuan-wen Wang, Jin Huk Choi, Miguel San Miguel, Sarah Grace McAlpine, Jamie Russell, Sara Ludwig, Xiaohong Li, Miao Tang, Xiaoming Zhan, Mihwa Choi, Tao Wang, Chun Hui Bu, Anne R. Murray, Eva Marie Y. Moresco, Emre E. Turer, Bruce Beutler
Format: Article
Language:English
Published: The Company of Biologists 2018-09-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/11/9/dmm035923