Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering
Summary: The application of machine learning toward DNA encoded library (DEL) technology is lacking despite obvious synergy between these two advancing technologies. Herein, a machine learning algorithm has been developed that predicts the conversion rate for the DNA-compatible reaction of a buildin...
Main Authors: | Ke Li, Xiaohong Liu, Sixiu Liu, Yulong An, Yanfang Shen, Qingxia Sun, Xiaodong Shi, Wenji Su, Weiren Cui, Zhiqiang Duan, Letian Kuai, Hongfang Yang, Alexander L. Satz, Kaixian Chen, Hualiang Jiang, Mingyue Zheng, Xuanjia Peng, Xiaojie Lu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-06-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220303278 |
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