Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope
The nuclear pore complex (NPC) mediates nucleocytoplasmic transport through the nuclear envelope. How the NPC assembles into this double membrane boundary has remained enigmatic. Here, we captured temporally staged assembly intermediates by correlating live cell imaging with high-resolution electron...
Main Authors: | Shotaro Otsuka, Khanh Huy Bui, Martin Schorb, M Julius Hossain, Antonio Z Politi, Birgit Koch, Mikhail Eltsov, Martin Beck, Jan Ellenberg |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/19071 |
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