RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases

RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases

For transcription through chromatin, RNA polymerase (Pol) II associates with elongation factors (EFs). Here we show that many EFs crosslink to RNA emerging from transcribing Pol II in the yeast Saccharomyces cerevisiae. Most EFs crosslink preferentially to mRNAs, rather than unstable non-coding RNAs...

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Bibliographic Details
Main Authors: Sofia Battaglia, Michael Lidschreiber, Carlo Baejen, Phillipp Torkler, Seychelle M Vos, Patrick Cramer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-05-01
Series:eLife
Subjects:
RNA polymerase II
transcription elongation
CTD Kinases
chromatin
PAR-CLIP
Online Access:https://elifesciences.org/articles/25637

Internet

https://elifesciences.org/articles/25637

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